Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Employed in the therapy of numerous myeloma. Its synthesis or analyze is very important for guaranteeing the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular kinds of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats various cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the manufacturing system and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to take care of breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the procedure of breast cancer. A variety (4S of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers which include ovarian, breast, and lung cancer.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal most cancers and smaller cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have many purposes, including 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of assorted gluconic acid derivatives, which happen to be Employed in food items, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).